BREAKTHROUGH results from a pioneering technology designed and built near Warrington promise smaller, cheaper therapy machines that could revolutionise cancer treatment.
New technology, developed at the STFC Daresbury Laboratory, could also pave the way for cleaner, safer nuclear reactors in the future.
The pioneering EMMA (Electron Model for Many Applications) accelerator – built at Daresbury – is a prototype for a brand new type of particle accelerator that will massively impact fundamental science by changing the way such accelerators across the world are designed and built in the future.
Initial experimental results from EMMA, confirm the proof of principle underlying its technology.
Existing accelerators have already had a profound beneficial impact upon society, with their wide range of uses in industry, medicine and basic science – including development of the MRI and X-rays. But they operate on principles developed more than 50 years ago and their potential is limited by their sheer size, complexity and cost.
EMMA represents a breakthrough. Based on innovative concepts never tried before, EMMA’s technology is more compact, cost effective and operationally simpler, allowing the more widespread use of accelerators to tackle some of the most difficult problems facing society.
The beneficial role of nuclear article therapy of cancers, particularly in the treatment of radiation-resistant and awkwardly sited tumours, is well known. It is therefore hoped that in the future this technology will allow hospitals to implement a newer and more effective form of beam therapy to help cure some of the most difficult cancers.
EMMA was designed by an international consortium of scientists as part of the CONFORM project, which includes the Universities of Manchester, Oxford, Surrey, Imperial, Brunel, Liverpool and Huddersfield, STFC, the Cockcroft and John Adams Institutes, as well as a number of international partners which include the Brookhaven National Laboratory and Fermilab in the US, and TRIUMF in Canada.
The ground-breaking concept is based on a ring of magnets which use their combined magnetic field simultaneously to steer and focus the electron beam around the machine. The strength of this magnetic field increases steeply as the beam spirals outwards while it is accelerated to 20 million electron volts around the ring.
Due to the strength of the magnetic focussing, the displacement of the beam as it accelerates and spirals around, the ring is much smaller than in any equivalent accelerator. As a result, EMMA’s ring of magnets is much more compact and it is easier to accelerate the beam.
The electron beam that is injected into EMMA is generated by another accelerator system operated by STFC at Daresbury, known as ALICE (Accelerators and Lasers In Combined Experiments), which is also based upon a mode of operation that drastically minimises the power needed to accelerate the beams.
Daresbury’s Professor Susan Smith said: “Better, cheaper accelerators could, in the future, increase access to improved medical treatment, provide better security scanning and create new solutions to tackle the energy crisis – as well as providing technology for the next generation of physics experiments. STFC has provided significant support for the construction of EMMA and now supports the experimental commissioning and characterisation of the accelerator.”
Dr Andrzej Kacperek, Head of Cyclotron at the Clatterbridge Centre for Oncology said: “From its origins, the development of the EMMA project has been pursued with an awareness of its role in particle therapy of cancers. Although enormous improvements have made in radiotherapy techniques using X-ray beams over last decades, the advantage of particle beams remains undiminished. EMMA’s technology reflects the need for a compact design, both in size and weight, that clinical centres require, with the ability to be used with a gantry system, which transports the beam from any angle around the patient, and the sophisticated beam control necessary to allow ‘painting’ of the tumour volume.”
A detailed paper on the new development can be viewed online at the Nature Physics website at www.nature.com/nphys/index.html
Pictures: Two views of EMMA.
Technology boost for cancer care
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